科研成果
  获奖  
  论文  
  专著  
  专利  
  新品种  
  软件著作权  
  成果转化  
  · 最新动态
  · 人才招聘
  · 专题
  · 科普旅游
  · 学会学报
  · 信息服务
  您现在的位置:首页 > 科研成果 > 论文
 
论文编号:
作者:
作者: Yuyi Yang,Chen Xu,Xinhua Cao,Hui Lin,Jun Wang*
作者所在部门:
作者所在部门:
通讯作者:
通讯作者: Jun Wang*
刊物名称:
刊物名称: Ecotoxicology
论文题目:
论文题目: Antibiotic resistance genes in surface water of eutrophic urban lakes are related to heavy metals, antibiotics, lake morphology and anthropic impact
摘要:
摘要:

Urban lakes are impacted by heavy human activities and represent potential reservoirs for antibiotic resistance genes. In this study, six urban lakes in Wuhan, central China were selected to analyze the distribution of sulfonamide resistance (sul) genes, tetracycline resistance (tet) genes and quinolone resistance (qnr) genes and their relationship with heavy metals, antibiotics, lake morphology and anthropic impact. sul1 and sul2 were detected in all six lakes and dominated the types of antibiotic resistance genes, which accounted for 86.28–97.79% of the total antibiotic resistance gene abundance. For eight tested tet genes, antibiotic efflux pumps (tetA, tetB, tetC, and tetG) genes were all observed in six lakes and had higher relative abundance than ribosomal protection protein genes (tetM and tetQ). For 4 plasmid mediated quinolone resistance genes, only qnrD is found in all six lakes. The class I integron (intI1) is also found to be a very important media for antibiotic resistance gene propagation in urban lakes.The results of redundancy analysis and variation partitioning analysis showed that antibiotic and co-selection with heavy metals were the major factors driving the propagation of antibiotic resistance genes in six urban lakes. The heavily eutrophic Nanhu Lake and Shahu Lake which located in a high density building area with heavy human activities had the higher relative abundance of total antibiotic resistance genes. Our study could provide a useful reference for antibiotic resistance gene abundance in urban lakes with high anthropic impact.

年: 2017
卷:
期:
页: DOI 10.1007/s10646-017-1814-3
收录类别:
影响因子:
论文出处:
论文出处:
外单位作者单位:
外单位作者单位:
备注:

关闭窗口